​The manufacturer of Pepaxto^® (melphalan flufenamide) has removed the drug from the market due to safety concerns. Based on this decision, AmeriHealth will archive Medical Policy #08.01.78b: Melphalan flufenamide (Pepaxto^®) as of January 1, 2022.

HCPCS code J9247 Injection, melphalan flufenamide, 1mg, will be set up as Experimental/Investigational and included in our Experimental/Investigational Services policy #12.01.01.

You can read about the decision on our Medical and Claim Payment Policy Portal or on the manufacturer's website.